1. End of Ordovician Extinction (~444 million years ago)Around 86% of species extinct due to intense glacial periods and climate changes affecting marine life.2. Late Devonian Extinction (~360 million years ago)About 75% species lost due to rapid global cooling caused by land plants' growth impacting climate and ocean chemistry.3. End Permian Extinction (~250 million years ago)Known as "The Great Dying," 96% of marine species and 70% terrestrial species went extinct due to massive volcanic activity causing global warming, ocean acidification, and acid rain.4. End Triassic Extinction (~200 million years ago)About 80% of species disappeared from volcanic activity and climate changes, setting stage for dinosaur domination.5. End Cretaceous Extinction (~65 million years ago)76% species extinct, including all non-avian dinosaurs, caused by an asteroid impact and volcanic activity causing rapid climate disruption[tex].[/tex]