Amino acids are the building blocks of proteins, and the order and type of amino acids in a protein directly affect its structure and function. There are 20 different types of amino acids, and each one has a unique R group (side chain) that influences how the protein will fold and behave.When amino acids are linked together by peptide bonds, they form a polypeptide chain. This chain doesn’t stay flat—it folds into complex shapes due to interactions between the R groups. These shapes are called the secondary, tertiary, and sometimes quaternary structures of proteins.If the amino acids are arranged correctly, the protein folds into a functional shape. If even one amino acid is wrong, the protein might fold incorrectly, and that can lead to serious diseases. For example, in sickle cell anemia, a single amino acid change causes hemoglobin to form the wrong shape, making red blood cells stiff and curved instead of soft and round.Amino acids also determine how a protein behaves. Some are hydrophobic (avoid water), and some are hydrophilic (attracted to water). These properties help the protein fold properly and function inside the cell.In short, amino acids decide a protein’s shape, behavior, and function. Without the right amino acids in the right order, the body can’t make proteins correctly—and since proteins do most of the work inside cells, this can affect nearly every system in the body.