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In Chemistry / Senior High School | 2025-05-19

What is a unique property of Bence Jones protein when subjected to heat?

Asked by mariojannelle6951

Answer (1)

A unique property of Bence Jones protein when subjected to heat is that it precipitates (forms a solid) at around 50-60°C but redissolves when the temperature is raised above 70°C.Bence Jones proteins are light chains of immunoglobulins found in the urine of patients with multiple myeloma. When heated, these proteins first denature and form insoluble aggregates at intermediate temperatures (50-60°C), causing precipitation. However, upon further heating to higher temperatures (above 70°C), the aggregates dissolve again, making this reversible heat precipitation a distinctive diagnostic feature.

Answered by CloudyClothy | 2025-05-24