Answer:The central conflict between the families of Romeo and Juliet is a longstanding feud between the Montagues (Romeo's family) and the Capulets (Juliet's family). This deep-rooted enmity has caused ongoing violence and hatred between the two noble families in Verona. The reason for the feud is not explicitly mentioned in the play, but it creates a major obstacle for Romeo and Juliet’s relationship, as their love is forbidden due to their family ties. This conflict ultimately leads to tragic consequences for both families.